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Pharmacology and Therapeutics (PHAR)

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Pharmacology and Therapeutics (PHAR)

Location

Location

  • McIntyre Medical Building
  • 3655 Promenade Sir William Osler
  • Montreal, Quebec H3G 1Y6
  • Telephone: 514-398-3623
  • Website:

About Pharmacology and Therapeutics

About Pharmacology and Therapeutics

Pharmacology is the science that deals with all aspects of drugs and their interactions with living organisms. Thus, it involves the physical and chemical properties of drugs, their biochemical and physiological effects, mechanisms of action, pharmacokinetics, and therapeutic and other uses. Since the word 鈥渄rug鈥 encompasses all chemical substances that produce an effect on living cells, it is evident that pharmacology is a very extensive subject. Pharmacology is a multidisciplinary science. It has developed its own set of principles and methods to study the mode of the action of drugs, but it has also utilized many techniques and approaches from various disciplines including biochemistry, physiology, anatomy and molecular biology, as well as others. Pharmacology encompasses a number of different areas such as pharmacogenomics, molecular biology, bioinformatics, neuropharmacology, reproductive pharmacology, endocrine pharmacology, receptor pharmacology, cardiovascular pharmacology, toxicology, developmental pharmacology, autonomic pharmacology, biochemical pharmacology, and therapeutics.

Training in pharmacology is conducted at both the undergraduate and graduate levels. Because of its breadth, students may be attracted to the subject from a variety of viewpoints; this includes those completing a Bachelor's degree in any number of basic science disciplines, such as biology, zoology, chemistry, physics, biochemistry, microbiology, anatomy and physiology. At the undergraduate level, seven lecture courses are offered. A course involving research projects in pharmacology is also available to provide the student with the opportunity to get first-hand experience in a pharmacology research laboratory. These courses provide students with knowledge concerning the actions of drugs on living systems and insight into approaches to basic pharmacological research.

A Science Major Concentration in Biomedical Sciences is available to students pursuing the B.A. & Sc. degree. This Major Concentration is described under the Bachelor of Arts and Science section of this publication; see Bachelor of Arts and Science > Biomedical Sciences.

Note: This program was retired at the end of the 2008-09 academic year and no new students were accepted as of June 2009.

Pharmacology and Therapeutics (PHAR) Faculty

Pharmacology and Therapeutics (PHAR) Faculty

Chair
Hans H. Zingg
Emeritus Professors
Brian Collier; B.Sc., Ph.D.(Leeds)
Theodore Sourkes; Ph.D.(C鈥檔ell)
Professors
Guillermina Almazan; Ph.D.(McG.)
Radan Capek; M.D., Ph.D.(Prague)
Paul B.S. Clarke; M.A.(Cant.), Ph.D.(Lond.)
A. Claudio Cuello; M.D.(Buenos Aires), M.A., D.Sc.(Oxf.) F.R.S.C.
Barbara Hales; M.Sc.(Phil. Coll. of Pharm. and Science), Ph.D.(McG.)
Dusica Maysinger; Ph.D.(S. Calif.)
Peter J. McLeod; M.D.(Manit.), F.R.C.P.(C.)
Alfredo Ribeiro-da-Silva; M.D., Ph.D.(Oporto)
Bernard Robaire; B.A.(Calif.), Ph.D.(McG.)
H. Uri Saragovi; Ph.D.(Miami)
Moshe Szyf; M.Sc., Ph.D.(Hebrew)
Jacquetta Trasler; M.D.,C.M., Ph.D.(McG.)
Daya R. Varma; M.D.(Lucknow), Ph.D.(McG.)
Hans H. Zingg; M.D., Ph.D.(McG.)
Associate Professors
Daniel Bernard; Ph.D.(Johns H.)
Derek Bowie; B.Sc., Ph.D.(Lond.)
Terence H茅bert; M.Sc.(Windsor), Ph.D.(Tor.)
Anne McKinney; Ph.D.(Ulster)
Stanley Nattel; B.Sc., M.D.,C.M.(McG.)
Ante L. Padjen; M.D., M.Sc., D.Sc.(Zagreb)
Betty I. Sasyniuk; B.S.P., Ph.D.(Manit.)
Edith A. Zorychta; B.Sc.(St. FX), M.Sc., Ph.D.(McG.)
Assistant Professors
Greg Miller; Ph.D.(W. Ont.)
Jason Chaim Tanny; Ph.D.(Harv.)
Associate Members
Moulay Alaoui-Jamali; Ph.D.(Sorbonne)
Gerald Batist; M.D.,C.M.(McG.)
Martine Culty; Ph.D.(Fr.)
Giovanni Di Battista; B.Sc., Ph.D.(Montr.)
Lesley Fellows; M.D.(McG.), Ph.D.(Oxf.)
Pierre Fiset; M.D.(Laval), F.R.C.P.S.(C).
Serge Gauthier; M.D.(Montr.)
Timothy Geary; Ph.D.(Mich.)
Bertrand Jean-Claude; M.Sc.(Moncton), Ph.D.(McG.)
Sarah Kimmins; Ph.D.(Dal.)
Stephane Laporte; Ph.D.(Sher.)
Cristian O鈥橣laherty; Ph.D.(McG.)
Vassilios Papadopoulos; Ph.D.(Universit茅 Pierre et Marie Curie)
Roger Prichard; B.Sc., Ph.D.(N.S.W.)
Yoram Shir; M.D.(Israel), Ph.D.(Johns H.)
Laura Stone; Ph.D.(Minn.)
Simon Rousseau; Ph.D.(Laval)
Remi Quirion; M.Sc., Ph.D.(Sher.)
Marc Ware; M.D.(Univ. West Indies, Kingston, Jamaica)
Xiang-Jiao Yang; Ph.D.(Shanghai)
Adjunct Professors
Bruce Allen; Ph.D.(Br. Col.)
Martin Bruno; Ph.D.(McG.)
Sylvain Chemtob; M.D.(Montr.), Ph.D.(McG.)
Yves De Koninck; Ph.D.(McG.)
Lorella Garofalo; Ph.D.(McG.)
Jennifer M.A. Laird; Ph.D.(Brist.)
Joseph Mancini; M.Sc., Ph.D.(McG.)
Graciela Pineyro; M.D.(Uruguay), Ph.D.(McG.)
Deborah Slipetz; Ph.D.(McG.)
Faculty of Science—2010-2011 (last updated Apr. 22, 2010) (disclaimer)

Bachelor of Science (B.Sc.) - Minor Pharmacology (24 credits)

The Minor Pharmacology is intended for students registered in a complementary B.Sc. program who are interested in a focused introduction to specialized topics in pharmacology to prepare them for professional schools, graduate education, or entry into jobs in industry or research institutes. Students should declare their intent to enter the Minor in Pharmacology at the beginning of their U2 year. They must consult with, and obtain the approval of, the Coordinator for the Minor Program in the Department of Pharmacology and Therapeutics. (Please contact the coordinator: Dr. Terry H茅bert; terence.hebert [at] mcgill.ca; 514-398-1398).

All courses in the Minor Program must be passed with a minimum grade C or better. Generally, no more than 6 credits of overlap are permitted between the Minor and the primary program.

Required Courses (12 credits)

PHAR 300 (3) Drug Action
PHAR 301 (3) Drugs and Disease
PHAR 562 (3) General Pharmacology 1
PHAR 563 (3) General Pharmacology 2

Complementary Courses (12 credits)

12 credits selected as follows:

3 credits, one of:

BIOC 212 (3) Molecular Mechanisms of Cell Function
BIOL 200 (3) Molecular Biology
BIOL 201 (3) Cell Biology and Metabolism

3 credits, one of:

PHGY 209 (3) Mammalian Physiology 1
PHGY 210 (3) Mammalian Physiology 2

6 credits, chosen from:

* PHAR 504 can be taken with PHAR 503 only.

PHAR 303 (3) Principles of Toxicology
PHAR 503* (3) Drug Design and Development 1
PHAR 504* (3) Drug Design and Development 2
PHAR 558 (3) Pharmacology Selected Topics
PHAR 599 (6) Pharmacology Research Project
Faculty of Science—2010-2011 (last updated Apr. 22, 2010) (disclaimer)

Bachelor of Science (B.Sc.) - Major Pharmacology (65 credits)

This program incorporates extensive studies in Pharmacology with a strong component of related biomedical sciences, providing a solid preparation for employment opportunities or for entry into graduate or professional training programs. Students must consult an adviser upon entering the program and at the beginning of U2 to verify courses and progress. Additional consultation at regular intervals is encouraged.

U1 Required Courses (19 credits)

BIOL 200 (3) Molecular Biology
CHEM 212 (4) Introductory Organic Chemistry 1
CHEM 222 (4) Introductory Organic Chemistry 2
PHGY 209 (3) Mammalian Physiology 1
PHGY 210 (3) Mammalian Physiology 2
PHGY 212 (1) Introductory Physiology Laboratory 1
PHGY 213 (1) Introductory Physiology Laboratory 2

U2 Required Courses (19 credits)

BIOC 311 (3) Metabolic Biochemistry
BIOL 202 (3) Basic Genetics
BIOL 301 (4) Cell and Molecular Laboratory
PHAR 300 (3) Drug Action
PHAR 301 (3) Drugs and Disease
PHAR 303 (3) Principles of Toxicology

U3 Required Courses (12 credits)

PHAR 503 (3) Drug Design and Development 1
PHAR 558 (3) Pharmacology Selected Topics
PHAR 562 (3) General Pharmacology 1
PHAR 563 (3) General Pharmacology 2

Complementary Courses (15 credits)

15 credits selected as follows:

3 credits selected from:

ANAT 212 (3) Molecular Mechanisms of Cell Function
BIOC 212 (3) Molecular Mechanisms of Cell Function
BIOL 201 (3) Cell Biology and Metabolism

3 credits selected from:

CHEM 203 (3) Survey of Physical Chemistry
CHEM 204 (3) Physical Chemistry/Biological Sciences 1

3 credits selected from:

BIOL 373 (3) Biometry
MATH 203 (3) Principles of Statistics 1
PSYC 204 (3) Introduction to Psychological Statistics

6 credits selected from the following upper-level science courses:

Committee approval is required to substitute an upper-level science course not in the list below.

PHAR 599D1 and PHAR 599D2 are taken together.

* Note: Students may take either ANAT 458 or BIOC 458.

** Note: Students may take either CHEM 504 or PHAR 504.

ANAT 321 (3) Circuitry of the Human Brain
ANAT 365 (3) Cellular Trafficking
ANAT 458* (3) Membranes and Cellular Signaling
BIOC 312 (3) Biochemistry of Macromolecules
BIOC 450 (3) Protein Structure and Function
BIOC 454 (3) Nucleic Acids
BIOC 455 (3) Neurochemistry
BIOC 458* (3) Membranes and Cellular Signaling
BIOL 300 (3) Molecular Biology of the Gene
BIOL 303 (3) Developmental Biology
BIOL 306 (3) Neural Basis of Behaviour
BIOL 314 (3) Molecular Biology of Oncogenes
BIOT 505 (3) Selected Topics in Biotechnology
CHEM 302 (3) Introductory Organic Chemistry 3
CHEM 502 (3) Advanced Bio-Organic Chemistry
CHEM 504** (3) Drug Design and Development 2
EXMD 504 (3) Biology of Cancer
EXMD 511 (3) Joint Venturing with Industry
MIMM 314 (3) Immunology
MIMM 387 (3) Applied Microbiology and Immunology
MIMM 414 (3) Advanced Immunology
NEUR 310 (3) Cellular Neurobiology
PATH 300 (3) Human Disease
PHAR 504** (3) Drug Design and Development 2
PHAR 599D1 (3) Pharmacology Research Project
PHAR 599D2 (3) Pharmacology Research Project
PHGY 311 (3) Channels, Synapses & Hormones
PHGY 312 (3) Respiratory, Renal, & Cardiovascular Physiology
PHGY 313 (3) Blood, Gastrointestinal, & Immune Systems Physiology
PHGY 314 (3) Integrative Neuroscience
PHGY 520 (3) Ion Channels
PSYC 311 (3) Human Cognition and the Brain
Faculty of Science—2010-2011 (last updated Apr. 22, 2010) (disclaimer)

Bachelor of Science (B.Sc.) - Honours Pharmacology (74 credits)

The Honours program is designed as a preparation for graduate studies and research. In addition to the strong training provided by the Major program, it requires students to have direct research experience in a chosen area during their final year of study. Acceptance into the Honours program takes place in the Winter term of U2 and requires a CGPA of 3.30. Students who wish to enter the Honours program should follow the Major program; those who satisfactorily complete the first three terms with a CGPA of at least 3.30 and a mark of B or higher in core Pharmacology courses are eligible for admission. Applications can be obtained from the Office of the Department of Pharmacology in the McIntyre Medical Building or on the departmental website.

U1 Required Courses (19 credits)

* Students with prior credit for CHEM 212 may take an elective in place of this course.

BIOL 200 (3) Molecular Biology
CHEM 212* (4) Introductory Organic Chemistry 1
CHEM 222 (4) Introductory Organic Chemistry 2
PHGY 209 (3) Mammalian Physiology 1
PHGY 210 (3) Mammalian Physiology 2
PHGY 212 (1) Introductory Physiology Laboratory 1
PHGY 213 (1) Introductory Physiology Laboratory 2

U2 Required Courses (19 credits)

BIOC 311 (3) Metabolic Biochemistry
BIOL 202 (3) Basic Genetics
BIOL 301 (4) Cell and Molecular Laboratory
PHAR 300 (3) Drug Action
PHAR 301 (3) Drugs and Disease
PHAR 303 (3) Principles of Toxicology

U3 Required Courses (18 credits)

* PHAR 599D1 and PHAR 599D2 are taken together.

PHAR 503 (3) Drug Design and Development 1
PHAR 558 (3) Pharmacology Selected Topics
PHAR 562 (3) General Pharmacology 1
PHAR 563 (3) General Pharmacology 2
PHAR 599D1* (3) Pharmacology Research Project
PHAR 599D2* (3) Pharmacology Research Project

Complementary Courses (18 credits)

18 credits selected as follows:

3 credits selected from:

ANAT 212 (3) Molecular Mechanisms of Cell Function
BIOC 212 (3) Molecular Mechanisms of Cell Function
BIOL 201 (3) Cell Biology and Metabolism

3 credits selected from:

CHEM 203 (3) Survey of Physical Chemistry
CHEM 204 (3) Physical Chemistry/Biological Sciences 1

3 credits selected from:

BIOL 373 (3) Biometry
MATH 203 (3) Principles of Statistics 1
PSYC 204 (3) Introduction to Psychological Statistics

9 credits selected from the following upper-level science courses:

Committee approval is required to substitute an upper-level science course not in the list below.

* Note: Students may take either ANAT 458 or BIOC 458.

** Note: Students may take either CHEM 504 or PHAR 504.

ANAT 321 (3) Circuitry of the Human Brain
ANAT 365 (3) Cellular Trafficking
ANAT 458* (3) Membranes and Cellular Signaling
BIOC 312 (3) Biochemistry of Macromolecules
BIOC 450 (3) Protein Structure and Function
BIOC 454 (3) Nucleic Acids
BIOC 455 (3) Neurochemistry
BIOC 458* (3) Membranes and Cellular Signaling
BIOL 300 (3) Molecular Biology of the Gene
BIOL 303 (3) Developmental Biology
BIOL 306 (3) Neural Basis of Behaviour
BIOL 314 (3) Molecular Biology of Oncogenes
BIOT 505 (3) Selected Topics in Biotechnology
CHEM 302 (3) Introductory Organic Chemistry 3
CHEM 502 (3) Advanced Bio-Organic Chemistry
CHEM 504** (3) Drug Design and Development 2
EXMD 504 (3) Biology of Cancer
EXMD 511 (3) Joint Venturing with Industry
MIMM 314 (3) Immunology
MIMM 387 (3) Applied Microbiology and Immunology
MIMM 414 (3) Advanced Immunology
NEUR 310 (3) Cellular Neurobiology
PATH 300 (3) Human Disease
PHAR 504** (3) Drug Design and Development 2
PHGY 311 (3) Channels, Synapses & Hormones
PHGY 312 (3) Respiratory, Renal, & Cardiovascular Physiology
PHGY 313 (3) Blood, Gastrointestinal, & Immune Systems Physiology
PHGY 314 (3) Integrative Neuroscience
PHGY 520 (3) Ion Channels
PSYC 311 (3) Human Cognition and the Brain
Faculty of Science—2010-2011 (last updated Apr. 22, 2010) (disclaimer)
Faculty of Science—2010-2011 (last updated Apr. 22, 2010) (disclaimer)
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