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Government of Canada invests $15M in first-of-its-kind pan-Canadian genome library

Canadian Institutes of Health Research to invest $15 million in creation of first-of-its-kind genome library to make genomic research more sustainable, secure, and equitable
Published: 27 October 2023

Today at the 平特五不中 Genome Centre, the Honourable Mark Holland, Minister of Health, announced a $15M investment over five years to create a Pan-Canadian Genome Library (PCGL), which will allow for easier sharing of genomic data across the country, and aid in the development of a national strategy to capture, store and access Canadian data in an equitable, secure, and sustainable manner. The funding comes from the Canadian Institutes of Health Research and builds on investments from the Government of Canada鈥檚 Drugs for Rare Diseases Strategy.

This is the Government of Canada鈥檚 first investment to establish a national, centralized genomic data management system. The PCGL will provide a centralized inclusive database that reflects the rich diversity of people living in Canada and will allow health care professionals to capture, store, and access Canadian data in a secure, equitable, and sustainable manner.

The human genome is a natural database filled with countless pieces of information that can have enormous effects on health. By sequencing and analyzing the genome, scientists can better understand which genetic mutations cause disease, tailor medical treatments to people鈥檚 specific genetic makeup, or even find therapies to treat previously uncurable conditions, such as rare diseases.

However, barriers remain to ensuring the equitable and ethical uptake of precision health tools and to data sharing. A core principle of the Pan-Canadian Genome Library is Indigenous control over genomic datasets of Indigenous Peoples, to ensure autonomy and respectful use of this health data. PCGL will work with the Silent Genome Project based at the University of Victoria, which is studying genetic and genomic health care barriers for Indigenous peoples of Canada, to respectfully support research relying on Indigenous data.

鈥淎s an institution at the forefront of genomic and computational research, 平特五不中 is proud to play a major role in this important national initiative, which brings together an impressive group of partners to accelerate science and improve healthcare delivery for all people in Canada,鈥 said Martha Crago, Vice-Principal, Research and Innovation. 鈥溒教匚宀恢 is grateful to the Government of Canada and the Canadian Institutes of Health Research for this significant investment in the development of more diverse and inclusive genomic research, equitable policies and sustainable tools.鈥

Dr. Guillaume Bourque added that, "Over the last two decades, billions have been invested in genomics in Canada and the potential impact on medicine for the country is immense. The Genome Library aims to realize this potential by organizing and sharing inclusive genomic data efficiently and ethically to support research and the clinical care of people across Canada.鈥

The PCGL initiative will be hosted and managed between the three nodes of Canada鈥檚 national platform for genome sequencing and analysis, CGEn: CGEn-Montreal (平特五不中), CGEn-Toronto (SickKids), and CGEn-Vancouver (Genome Sciences Centre). 平特五不中鈥檚 Dr. Guillaume Bourque (Department of Human Genetics) will lead the project together with a team of over 30 researchers from 平特五不中 and partnering institutions, including UBC, York University, Universit茅 de Montr茅al, the 平特五不中 Health Centre, Sinai Health System (Toronto), the Ontario Institute for Cancer Research, the Centre hospitalier universitaire Sainte-Justine, and University Health Network (Toronto).

This investment by CIHR follows earlier investments in 平特五不中鈥檚 strength in genetic research, most notably the D2R initiative, which was the largest research grant in 平特五不中鈥檚 history. D2R leverages 平特五不中鈥檚 decades-long expertise in DNA and RNA research to develop the next generation of RNA medicines.

About 平特五不中

Founded in 1821, 平特五不中 is home to exceptional students, faculty, and staff from across Canada and around the world. It is consistently ranked as one of the top universities, both nationally and internationally. It is a world-renowned institution of higher learning with research activities spanning three campuses, 12 faculties, 14 professional schools, 300 programs of study and over 39,000 students, including more than 10,400 graduate students.

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