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Dae-Kyum, Kim (PhD)

Academic title(s): 

Assistant Professor

Dae-Kyum, Kim (PhD)
Contact Information
Email address: 
dae.k.kim [at] mcgill.ca
Department: 
Surgery
Division: 
Thoracic Surgery
Upper GI
Degree(s): 

PhD

Location: 
平特五不中 Health Centre (MUHC - Glen) - Royal Victoria Hospital
Research areas: 
Data Science
Precision Health
Graduate supervision: 

Are you currently supervising students? YES
Looking to supervise graduate students? YES
Looking to hire a Postdoctoral fellow? YES

Link(s): 
/thoracic/research-innovation/dr-dae-kyum-kims-lab
Current research: 

In going through these transitions between various fields, I gained strong expertise within both experimental and computational backgrounds, which has enabled me to design a novel functional genomics pipeline to identify new biomarkers for human disease. Now, as a new principal investigator at 平特五不中, I would like to further pursue the translation of functional genomics tools to precision medicine. By exploring novel approaches to evaluate proteome-scale gene overexpression effects under various conditions, I would like to find novel drug combinations to combat therapeutic resistance, especially DCF and FLOT therapeutic resistance for gastro-esophageal cancer.

Clinical Interests: 

Gastro-Esophageal Cancer

Group: 
Currently Recruiting Students: YES
Selected publications: 

1. Kim DK*, WellerB*, Lin CW*, Sheykhkarimli D*, Knapp JJ*, Dugied G*, 鈥�, Demeret C#, Vidal M#, Calderwood MA#, Roth FP#, Falter-Braun P#. A proteome-scale map of the SARS-CoV-2 human contactome. Nat Biotechnol. 2023 Jan;41(1):140-149.

2. Luck K*, Kim DK*, Lambourne L*, Spirohn K*, 鈥�, Tavernier J#, Hill DE#, Vidal M#, Roth FP#, Calderwood MA#. A reference map of the human binary protein interactome. Nature. 2020 Apr;580(7803):402鈥�8. PMCID: PMC7169983

3. Kim DK*, Lee J*, 鈥�, Gho YS. EVpedia: A community web portal for extracellular vesicles research. Bioinformatics. 2015 Mar 15;31(6):933鈥�9. PMCID: PMC4375401

4. Lim HJ*, Yoon H*, Kim H*, Kang YW, Kim JE, Kim OY, Lee EY, Twizere JC, Rak J#, Kim DK#. Extracellular vesicle proteomes shed light on the evolutionary, interactive, and functional divergence of their biogenesis mechanisms. Front Cell Dev Biol. 2021 Oct 1;9:734950. PMCID: PMC8517337

5. Yu J*, Sane S*, Kim JE*, Yun S*, Kim HJ, Jo KB, Wright JP, Khoshdoozmasouleh N, Lee K, Oh HT, Thiel K, Parvin A, Williams X, Hannon C, Lee H#, Kim DK#. Biogenesis and delivery of extracellular vesicles: harnessing the power of EVs for diagnostics and therapeutics. Frontiers in Molecular Biosciences. 2024 Jan 3:10:1330400.

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