Centre for RNA Sciences

Centre for RNA Sciences /rna/articles/rss en Exploring the RNA world to design and test novel therapeutic approaches /rna/article/exploring-rna-world-design-and-test-novel-therapeutic-approaches When Martin Sauvageau, PhD, isn’t developing therapeutic approaches for liver, pancreatic, and neurodegenerative diseases, you may find him at home in his kitchen cooking up classical French recipes or Asian cuisine. Or, more leisurely, considering the parallels between RNA cellular networks and how a city works architecturally. However, in the lab at the Institute of Clinical Research in Montreal (IRCM), he’s on a mission, researching the mysteries of long non-coding RNAs (lncRNA). Fri, 28 Apr 2023 20:37:30 +0000 Timothy Gouldson 636 at /rna Developing new therapeutics based on RNA targeting and gene editing /rna/article/developing-new-therapeutics-based-rna-targeting-and-gene-editing Many things have changed since Masad Damha, PhD, came to ƽ��岻�� 44 years ago to study chemistry (BSc ’83; PhD ’87), though with the launch of the ƽ��岻�� Centre for RNA Sciences (MCRS), he believes the passionate spirit of innovation that first drew him here from Nicaragua has only intensified. “When I joined Prof. Kelvin Ogilvie’s lab to pursue doctoral studies in nucleic acid chemistry, my main focus was chemical synthesis of RNA – a daunting task at that time,” recalls Prof. Damha. Mon, 28 Nov 2022 17:12:41 +0000 Wendy Helfenbaum 635 at /rna Using powerful computational methods to understand the role of RNA in human cancers /rna/article/using-powerful-computational-methods-understand-role-rna-human-cancers At first glance, studying the parasite that causes African sleeping sickness does not necessarily seem like an obvious path to studying the causes of cancer in humans. But for Hamed Najafabadi, PhD, there is a common thread. After earning his PhD at ƽ��岻��, he went to University of Toronto for a post-doctoral fellowship in new machine learning approaches. “When I look back, it’s very interesting how everything in my work connected to the regulation of RNA,” he says. Wed, 02 Nov 2022 19:43:44 +0000 Maureen McCarthy 634 at /rna Manufacturing biomaterials to enable research /rna/article/manufacturing-biomaterials-enable-research Amine Kamen, PhD, believes the new ƽ��岻�� Centre for RNA Sciences (MCRS) will promote collaboration and innovation between leading researchers across the University. Tue, 01 Nov 2022 19:27:17 +0000 Wendy Helfenbaum 633 at /rna From AIDS to COVID-19: The promise of RNA therapeutics /rna/article/aids-covid-19-promise-rna-therapeutics Anne Gatignol, PhD, has explored the molecular world of RNA and RNA viruses for more than 30 years. A virologist recognized internationally for her work on virus-cell interactions during HIV replication, she is a Professor in the Department of Medicine (Division of Experimental Medicine) and Department of Microbiology and Immunology in ƽ��岻��’s Faculty of Medicine and Health Sciences. Tue, 01 Nov 2022 19:25:02 +0000 Allyson Rowley 632 at /rna Single-cell fluorescence microscopy sheds light on stress-regulated gene mechanisms /rna/article/single-cell-fluorescence-microscopy-sheds-light-stress-regulated-gene-mechanisms When it comes to developing advanced technology to further scientific research, Maria Vera Ugalde, PhD, an Assistant Professor in the Department of Biochemistry at ƽ��岻��’s School of Biomedical Sciences, proves that necessity is the mother of invention. Tue, 01 Nov 2022 19:22:37 +0000 Maureen McCarthy 631 at /rna A conversation with ƽ��岻��’s ‘guru’ of mRNA /rna/article/conversation-mcgills-guru-mrna Canada’s leading expert on mRNA, Nahum Sonenberg, PhD, is the Gilman Cheney Chair in Biochemistry at ƽ��岻��’s Rosalind and Morris Goodman Cancer Institute. Prof. Sonenberg, who earned his PhD from the Weizmann Institute of Science in 1976, has dedicated more than 50 years to the study of RNA biology. His exploration of the mechanics of RNA translation and how it is regulated, both in normal conditions and in disease states, has improved science’s understanding of diseases including cancer, diabetes, autism and fragile X syndrome. Tue, 01 Nov 2022 03:17:04 +0000 Allyson Rowley 630 at /rna Maureen McKeague on how ƽ��岻��’s interdisciplinary team could uncover the multifaceted potential of artificial RNA /rna/article/maureen-mckeague-how-mcgills-interdisciplinary-team-could-uncover-multifaceted-potential-artificial Interdisciplinarity has always been central to the research of Maureen McKeague, PhD. As a joint Assistant Professor between the Department of Pharmacology and Therapeutics at the Faculty of Medicine and Health Sciences and the Department of Chemistry at the Faculty of Science at ƽ��岻��, her work intersects with medicine, chemistry and engineering. Wed, 26 Oct 2022 19:58:53 +0000 Jane O'Faherty 629 at /rna From the study of what dictates protein output from mRNAs, to blocking mRNA expression, ƽ��岻��’s Jerry Pelletier has storied history of RNA research /rna/article/study-what-dictates-protein-output-mrnas-blocking-mrna-expression-mcgills-jerry-pelletier-has Jerry Pelletier, PhD, a Professor at ƽ��岻��’s Department of Biochemistry and Department of Oncology, and a member of the Rosalind and Morris Goodman Cancer Institute, is a distinguished RNA biology researcher who brings a unique and significant focus on the developing area of RNA research as a co-founder of the ƽ��岻�� Centre for RNA Sciences. Wed, 26 Oct 2022 16:46:38 +0000 Justin Hand-Gregory 628 at /rna How RNA research could provide valuable insights into rare inherited tumours /rna/article/how-rna-research-could-provide-valuable-insights-rare-inherited-tumours-qa-william-foulkes William Foulkes, MBBS, PhD, is a James ƽ��岻�� Professor in the Departments of Medicine, Oncology and Human Genetics at ƽ��岻�� and a researcher-clinician who has practiced clinical genetics at ƽ��岻��-affiliated hospitals since 1996. Thu, 20 Oct 2022 21:30:10 +0000 Jane O'Faherty 625 at /rna