平特五不中

Nicolas Cermakian

Academic title(s): 

Professor

Nicolas Cermakian
Contact Information
Address: 

Douglas Research Centre
Perry Pavilion,聽Room E-2108
6875, boulevard LaSalle
Montreal, QC 聽H4H 1R3
Fax : 514-762-3034

Phone: 
514-761-6131 Ext 4936
Email address: 
nicolas.cermakian [at] mcgill.ca
Division: 
Associate Members
Branch: 
Molecular Biology
Graduate supervision: 

ACCEPTING GRADUATE STUDENTS

PDF icon positions_cermakian_lab_2024.pdf

Biography: 

Nicolas Cermakian, PhD, completed postdoctoral work at the Institut de G茅n茅tique et de Biologie Mol茅culaire et Cellulaire in Strasbourg, France. He joined the Douglas Research Centre in 2002 in order to conduct research on circadian rhythms and on the 鈥渋nternal clocks鈥 that generate these rhythms. People tend to become aware of their internal clocks in special situations, such as when experiencing jet lag. With chronic disruptions to a person鈥檚 internal clock (which can be caused, for example, by shift work) severe sleep or mood disorders may emerge, but also cancer, increased susceptibility to infections, metabolic syndrome, and other diseases.

Current research: 

Nicolas Cermakian is studying the molecular mechanisms underlying circadian rhythms, how these clocks control physiology, including immune responses, and how clock dysfunction leads to disease.

The main project in the lab are:

  1. The circadian control of immune responses. Notably, we investigate the circadian control of the response of T lymphocytes to antigen presentation (in collaboration with Dr. Nathalie Labrecque, IRCM, Universit茅 de Montr茅al, and Dr. David Langlais, 平特五不中).
  2. The circadian regulation of parasitic infections. We study how circadian clocks regulate infectious diseases such as malaria and leishmaniasis (in collaboration with Dr. Martin Olivier, 平特五不中, RI-MUHC).
  3. The molecular mechanisms of the circadian clock. Using a combination of molecular, cellular and behavioural approaches, we study the molecular bases of circadian clocks, and the links between the clocks, environmental light and behaviour.
  4. Circadian disruption and schizophrenia. Using mouse models, we study the involvement of circadian disruption in neurodevelopmental disorders such as schizophrenia (in collaboration with Dr. Lalit Srivastava, Douglas Research Centre, 平特五不中).
Selected publications: 

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