平特五不中

This year, the GCI master's students, doctoral students and post-doctoral fellows excelled in provincial and national funding opportunities. Together, 29 students were awarded 1.9M$ by the Fonds de Recherche du Qu茅bec (FRQ) and the Canadian Tri-Council Agencies. Below, we highlight some of the talented, hardworking trainees who earned these studentships. Each one of them studies a critical aspect of a different cancer type.

Mark Sorin was awarded the Vanier scholarship, a highly competitive and prestigious award that selects candidates for their academic excellence, involvement in leadership roles and the potential of their research. "My research focuses on the role of the tumour immune microenvironment in the context of lung cancer. We investigate how to improve the anti-tumour immune response in lung cancer patients receiving immunotherapy, " explains Mark, a doctoral student in the Walsh lab. The tumour microenvironment is one of GCI's central research focuses. It shows great promise in improving existing cancer therapies by targeting not only the cancer cells but also the cells that interact with them.

Joan Miguel Romero is an M.D.-Ph.D. candidate in the laboratory of George Zogopoulos. He was also awarded the very prestigious Vanier award for his research on pancreatic cancer. His personal story was a big motivator when it came to choosing his research topic: "My father passing from pancreatic cancer motivated me to become a physician-scientist and help people facing cancer". Joan Miguel strives to identify the patients that have good chances of responding to currently available therapies: "An important reason for 90% lethality rate of pancreatic cancer is that does not respond well to chemotherapies and immunotherapies. My Ph.D. project focuses on identifying subtypes of pancreatic cancer that may respond to immunotherapies". Knowing very well what cancer patients and their close ones might experience, Joan Miguel finds purpose in sharing cancer research:听"I am co-chair for the Research Information Outreach Team of the Canadian Cancer Society, Montreal Chapter. Working with an amazing group of volunteers, including our co-chair predecessors, we aim to make cancer research accessible to the general population through community outreach and awareness events. Being a part of this group and interacting with individuals and their families affected by cancer deepens my resolve to study this disease."

Rima Ezzidine is a Ph.D. candidate in Peter Siegel's laboratory. "I work on breast cancer that has metastasized to the leptomeninges, which are the membranes that surround the brain and spinal cord. My research aims at characterizing the role of a protein called CIRBP (Cold Inducible RNA Binding Protein) in facilitating breast cancer metastasis to the leptomeninges and identifying its targets in the process." Rima was awarded an FRQ-Sant茅 scholarship to pursue her essential research. "This knowledge may ultimately contribute to the prevention or treatment of leptomeningeal metastases.", concludes Rima.

Diana Berry was awarded a scholarship from FRQ-Sant茅 for her doctoral studies. Her research focuses on understanding the mechanisms underlying the response to skin cancer. "I aim to determine why some melanoma patients have an improved response to a class of immune therapies." Diana, who performs her research in Ian Watson'S laboratory, hopes that her findings might extend the reach of her drug of interest to patients suffering from other types of cancer. "Determining the mechanism behind how these patients respond to these drugs could provide the rationale to use them to treat a number of other cancers."

Marina Fukano was awarded a doctoral scholarship from the Canadian Institute of Health Research (CIHR) to study a complex aspect of a lethal form of breast cancer. "My Ph.D. project studies a subtype of breast cancer called Triple-Negative Breast Cancer (TNBC). I study how tumour heterogeneity, cancer cells that present distinct characteristics, found within a tumour can support tumour progression". In addition to working full time towards earning her Ph.D. in the laboratory of Morag Park, Marina is passionate about sharing knowledge about cancer research with everyone:" I am currently part of the RIOT (Research Information Outreach Team)-Montreal as well as the CEEHRC (Canadian, Epigenetics, Environment and Health Research Consortium Network) Knowledge Translation Training Committee, as I realized the importance of communicating what we do in cancer research with the general public and raising awareness of cancer and cancer research."

Camila Fraga Faraco earned FRQ-Sant茅 scholarship to fund her doctoral research in the laboratory of Alain Nepveu. Her research focuses on finding a new role for a known cancer-inducing protein: "My research project will demonstrate the role of a transcription factor as an auxiliary factor in DNA repair. This new role most likely contributes to the oncogenic potential of this protein. While it is difficult to inhibit its transcriptional activity, we can envisage the possibility of inhibiting its DNA repair activity", explains Camila. She stresses the importance to translate her research into therapies: "My work will lead to translational research into the development of novel therapeutic strategies for the treatment of patients whose cancer cells exhibit high expression of this auxiliary factor".

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Congratulations to all recipients! The list of all awardees is available below:

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Vanier Canada Graduate Scholarship Recipients

Joan Miguel Romero, Zogopoulos Lab

Mark Sorin, Walsh Lab.

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FRQ-Sant茅 2022-23 Recipients

Younes Medkour, FRQS Post-doctoral, Gigu猫re Lab

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Diana Berry, FRQS Doctoral, Watson Lab

Owen Chen, FRQS Doctoral, Teodoro Lab

Lysanne Desharnais, FRQS Doctoral, Quail & Walsh Lab

Rima Ezzeddine, FRQS Doctoral, Siegel Lab

Chu-Han Feng, FRQS Doctoral, Tremblay Lab

Camila Cristina Fraga Faraco, FRQS Doctoral, Nepveu Lab

Yu Gu, FRQS Doctoral, Muller Lab

Keerthana Harwalkar, FRQS Doctoral, Yamanaka Lab

Jiang Jialin, FRQS Doctoral, Huang Lab

Sherif Attalla, FRQS Doctoral, Muller Lab

Miranda Yu, FRQS Doctoral, Quail Lab

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Alexander Nowakowski, FRQS Master鈥檚, Siegel Lab

Sarah Petrecca, FRQS Master's, Quail Lab

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CIHR M.Sc. 2022-23 Recipients

Alexander Nowakowski, Siegel Lab

Reese Ladak, Sonenberg Lab

Mohammad Zafir Kaiser, Kazak Lab

Marie-脠ve Proulx, McCaffrey Lab

Sarah-Slim Diwan, Duchaine Lab

Annika Pedersen, Park Lab

Alice Nam, Muller Lab

Daniel Krauss, Teodoro Lab

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NSERC Doctoral 2022-23 Recipients

Faiz Hussain, Kazak Lab

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CIHR-Doctoral 2022-23 R茅cipients

Lysanne Desharnais, Quail Lab

Marina Fukano, Park Lab

Joan Miguel Romero, Zogopoulos Lab

Kayla Heney, Watson Lab

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Cole Foundation 2022-23 Recipient

Ana Maria Hincapie Restrepo, Tremblay Lab