/channels/taxonomy/term/2010/all en /channels/channels/news/quebec-siblings-rare-orphan-disease-lead-discovery-rare-genetic-diseases-296454 <p>Mutations in a gene involved in brain development have led to the discovery of two new neurodevelopmental diseases by an international team led by researchers at ƽÌØÎå²»ÖÐ and CHU Sainte-Justine Research Center.</p> <p>The first clues about the rare disorder arose after doctors were unable to diagnose why two siblings from Québec City were experiencing seizures and neurodevelopmental deficits. Desperate, the children’s family turned to Carl Ernst at the Douglas Mental Health University Institute in Montreal for answers.</p> Thu, 25 Apr 2019 15:06:05 +0000 webfull 148625 at /channels /channels/channels/news/new-insight-how-autism-might-develop-human-brain-287849 <p>In a study published in <em>Stem Cell Reports</em>, a ƽÌØÎå²»ÖÐ team of scientists led by Dr. Carl Ernst, researcher at the Douglas Hospital Research Centre, revealed a molecular mechanism that may play a role in the development of autism.</p> <p>By taking skin cells from patients and reprogramming those cells to become brain cells through genetic engineering, Dr. Ernst, graduate student Scott Bell, and Edward A. Fon and Thomas M. Durcan, colleagues at the Montreal Neurological Institute and Hospital, tracked how a brain cell with the patient’s own mutation develops improperly.</p> Tue, 26 Jun 2018 18:46:30 +0000 webfull 138760 at /channels /channels/news/mcgill-researchers-link-mutation-psychiatric-disease-218499 <p><span>ƽÌØÎå²»ÖÐ researchers have identified a small region in the genome that conclusively plays a role in the development of psychiatric disease and obesity. The key lies in the genomic deletion of brain-derived neurotrophic factor, or BDNF, a nervous system growth factor that plays a critical role in brain development.</span> Wed, 10 Oct 2012 16:52:21 +0000 webfull 87667 at /channels /channels/news/dr-carl-ernsts-research-featured-montreal-gazette-218516 <p>Rare genetic mutation linked to psychiatric illnesses, obesity </p> <h2></h2> <p>B Charlie Fidelman, GAZETTE Health Reporter October 8, 2012 </p> <p>MONTREAL — Grounding chronic illnesses and mental disorders in human DNA is like trying to tease out a giant riddle that’s complicated by the intricate relationship between biology and behaviour. Hundreds of genes have been associated with psychiatric conditions, some erroneously, and they were not confirmed.</p> Thu, 11 Oct 2012 17:58:02 +0000 webfull 87704 at /channels /channels/news/six-new-canada-research-chairs-mcgill-218528 <p>ƽÌØÎå²»ÖÐ is proud to announce that six new Canada Research Chairs have been awarded and nine chairs have been renewed, bringing a total of over $15 million to the university for research in fields ranging from social inequalities in child health to experimental optomechanics over the next five to seven years. Fri, 12 Oct 2012 17:47:51 +0000 webfull 87733 at /channels /channels/news/autism-spectrum-disorders-share-common-molecular-causes-239436 Thu, 09 Oct 2014 18:03:18 +0000 webfull 105783 at /channels