平特五不中

Canada-U.S. study recommends聽 in Journal of Clinical Endocrinology & Metabolism recommends young people be screened for low vitamin D levels.

Insufficient vitamin D can stunt growth and foster weight gain during puberty, according to a new study published in the Journal of Clinical Endocrinology & Metabolism. Even in sun-drenched California, where scientists from the 平特五不中 Health Centre (MUHC) and the University of Southern California conducted their study, vitamin D deficiency was found to cause higher body mass and shorter stature in girls at the peak of their growing spurt.

While lack of vitamin D is common in adults and has been linked to diseases such as osteoporosis, cancer and obesity, until this study, little was known about the consequences of insufficient vitamin D in young people. The research team measured vitamin D in girls aged 16 to 22 using a simple blood test (25-hydroxy vitamin D). They also assessed body fat and height to determine how vitamin D deficiency could affect young women鈥檚 health.

鈥淭he high prevalence of vitamin D insufficiency in young people living in a sun-rich area was surprising,鈥� says study lead author, , co-director of the Musculoskeletal Axis of the Research Institute of the MUHC. 鈥淲e found young women with vitamin D insufficiency were significantly heavier, with a higher body mass index and increased abdominal fat, than young women with normal levels.鈥�

Vitamin D fosters growth, healthier weight
The researchers examined 90 Caucasian and Hispanic girls and discovered that young women with normal vitamin D levels were on average taller than peers deficient in vitamin D. Yet in contrast to what鈥檚 been previously reported in older women, their investigation found no association between lack of vitamin D and bone strength.

鈥淎lthough vitamin D is now frequently measured in older adults, due to a higher level of awareness in this population, it is rarely measured in young people 鈥� especially healthy adolescents,鈥� says Dr. Kremer.

鈥淐linicians need to identify vitamin D levels in younger adults who are at risk by using a simple and useful blood test,鈥� says the co-author, Dr. Vicente Gilsanz, head of musculoskeletal imaging at the Children鈥檚 Hospital Los Angeles of the University of Southern California.

鈥淏ecause lack of vitamin D can cause fat accumulation and increased risk for chronic disorders later in life, further investigation is needed to determine whether vitamin D supplements could have potential benefits in the healthy development of young people,鈥� added Dr. Gilsanz.

About the study:
鈥淰itamin D Status and its Relationship to Body Fat, Final Height and Peak Bone Mass in Young Women,鈥� published in the Journal of Clinical Endocrinology & Metabolism, was authored by Richard Kremer of the 平特五不中 Health Centre, Patricia P. Campbell and Vicente Gilsanz of the Children鈥檚 Hospital Los Angeles of the University of Southern California, and Timothy Reinhardt of the U.S. Department of Agriculture鈥檚 National Animal Disease Center.

Partners in research:
This work was supported by the U.S, Department of the Army; the National Institutes of Health (a part of the U.S. Department of Health and Human Services); the Natural Sciences and Engineering Research Council of Canada (NSERC); and the Dimensional Fund Advisors Canada Inc (a subsidiary of U.S.-based Dimensional Fund Advisors).

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About the

The Research Institute of the 平特五不中 Health Centre (RI MUHC) is a world-renowned biomedical and health-care hospital research centre. Located in Montreal, Quebec, the institute is the research arm of the MUHC, the university health center affiliated with the Faculty of Medicine at 平特五不中 University. The institute supports over 600 researchers, nearly 1200 graduate and post-doctoral students and operates more than 300 laboratories devoted to a broad spectrum of fundamental and clinical research. The Research Institute operates at the forefront of knowledge, innovation and technology and is inextricably linked to the clinical programs of the MUHC, ensuring that patients benefit directly from the latest research-based knowledge.

The Research Institute of the MUHC is supported in part by the Fonds de la recherche en sant茅 du Qu茅bec.

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