Special Seminar
Dr. St茅phane Gasman, Ph.D, Directeur de Recherche 脿 l'INSERM,
Institut des Neurosciences Cellulaires et Int茅grative (INCI) of the
Universit茅 de Strasbourg will give a talk entitled "Molecular
mechanisms of coupling between exocytosis and endocytosis in
neuroendocrine cells"
In neuroendocrine cells, release of hormones and neuropeptides
occurs through calcium-dependent exocytosis of large dense-core
secretory granules. Exocytosis is then followed by compensatory
endocytosis, yet how these two processes are coupled remains
largely unexplored. Dr. St茅phane Gasman, Directeur de Recherche 脿
l'INSERM, Universit茅 de Strasbourg has been a leading expert on
defining how exocytosis is temporally and spatially coupled to
endocytosis. His current research focuses on actin dynamics and Rho
GTPases, which appear to play an essential role in membrane
trafficking and are attractive candidates as possible regulators of
exo-endocytosis.