平特五不中

Peter E. Braun

Professor Emeritus
Department of Biochemistry

Myelinology and Inhibition of Neural Regeneration

peter.braun [at] mcgill.ca

1967 - PhD, University of California (Berkeley)

Please note: no longer training graduate students or post-doctoral fellows

Research Interests

Our broadly-based research interests are in developmental neurobiology, neural regeneration, and demyelinating disorders of the nervous system. Our current investigative endeavours are focused on:

  • 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP), a protein that appears early in CNS development, a determinant of oligodendrocyte differentiation and maturation that entrains early stages of myelinogenesis; we seek to understand how CNP participates in these complex events, and how one might capitalize on this knowledge to enhance therapeutic remyelination in diseased CNS.
  • Molecules associated with myelin that provide a non-permissive environment for nerve re-growth in the injured CNS; therapeutic strategies to overcome these inhibitors.

We employ a combination of biochemistry, cellular neurobiology and recombinant DNA technologies to address these interests. Our recently generated transgenic mouse models facilitate these endeavours.

Publications -

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